2. Metabolic Disease

Metabolic Disease

Metabolic Disease

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Metabolic diseases is defined by a constellation of interconnected physiological, biochemical, clinical, and metabolic factors that directly increases the risk of cardiovascular disease, type 2 diabetes mellitus, and all cause mortality. Associated conditions include hyperuricemia, fatty liver (especially in concurrent obesity) progressing to nonalcoholic fatty liver disease, polycystic ovarian syndrome (in women), erectile dysfunction (in men), and acanthosis nigricans. Metabolic disease modeling is an essential component of biomedical research and a mandatory prerequisite for the treatment of human disease. Somatic genome editing using CRISPR/Cas9 might be used to establish novel metabolic disease models.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-B0389S21
    D-Glucose-13C,d2 478529-33-8 98%
    D-Glucose-13C,d2 is the deuterium and 13C labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical sig
    D-Glucose-13C,d2
  • HY-B0389S22
    D-Glucose-13C2,d2 157171-80-7 98%
    D-Glucose-13C2,d2 is the deuterium and 13C labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical si
    D-Glucose-13C2,d2
  • HY-B0389S23
    D-Glucose-d2-1 478529-48-5 98%
    D-Glucose-d2-1 is the deuterium labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling mol
    D-Glucose-d2-1
  • HY-B0389S24
    D-Glucose-d4 478529-49-6 ≥99.0%
    D-Glucose-d4 is the deuterium labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molec
    D-Glucose-d4
  • HY-B0389S25
    D-Glucose-13C,d1 83379-46-8 98%
    D-Glucose-13C,d is the deuterium and 13C labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical sig
    D-Glucose-13C,d1
  • HY-B0389S26
    D-Glucose-d2-2 1009828-82-3 98%
    D-Glucose-d2-2 is the deuterium labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling mol
    D-Glucose-d2-2
  • HY-B0389S30
    D-Glucose-18O-1 98%
    D-Glucose-18O-1 is the 18O labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecule
    D-Glucose-18O-1
  • HY-B0389S31
    D-Glucose-18O-2 98%
    D-Glucose-18O-2 is the 18O labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecule
    D-Glucose-18O-2
  • HY-B0389S32
    D-Glucose-18O-3 98%
    D-Glucose-18O-3 is the 18O labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecule
    D-Glucose-18O-3
  • HY-CE00276A
    3,8-Dioxooct-5-enoyl-CoA 1372804-06-2 98%
    3,8-Dioxooct-5-enoyl-CoA (3,8-Dioxooct-5-enoyl-coenzyme A) is an acyl-CoA.
    3,8-Dioxooct-5-enoyl-CoA
  • HY-CE00503A
    2-Octenoyl-CoA 71629-68-0 98%
    2-Octenoyl-CoA (2-Octenoyl-coenzyme A) is a coenzyme A derivative.
    2-Octenoyl-CoA
  • HY-CE00734A
    12-Alpha-hydroxy-3-oxochola-4,6-dien-24-oyl-CoA 1931931-89-3 98%
    12-Alpha-hydroxy-3-oxochola-4,6-dien-24-oyl-CoA (12-Alpha-hydroxy-3-oxochola-4,6-dien-24-oyl-coenzyme A) is a steroidal acyl-CoA.
    12-Alpha-hydroxy-3-oxochola-4,6-dien-24-oyl-CoA
  • HY-CE00800A
    3-(4-Methylpent-3-en-1-yl)pent-2-enedioyl-CoA 1245946-43-3 98%
    3-(4-Methylpent-3-en-1-yl)pent-2-enedioyl-CoA (3-(4-Methylpent-3-en-1-yl)pent-2-enedioyl-coenzyme A) is a 2-enoyl-CoA.
    3-(4-Methylpent-3-en-1-yl)pent-2-enedioyl-CoA
  • HY-N0215S13
    L-Phenylalanine-d1 54793-54-3 98%
    L-Phenylalanine-d is the deuterium labeled L-Phenylalanine. L-Phenylalanine ((S)-2-Amino-3-phenylpropionic acid) is an essential amino acid isolated from Escherichia coli. L-Phenylalanine is a α2δ subunit of voltage-dependent Ca+ channels antagonist with a Ki of 980 nM. L-phenylalanine is a competitive antagonist for the glycine- and glutamate-binding sites of N-methyl-D-aspartate receptors (NMDARs) (KB of 573 μM ) and non-NMDARs, respectively. L-Phenylalanine is widely used in the production of food flavors and pharmaceuticals.
    L-Phenylalanine-d1
  • HY-N0229S11
    L-Alanine-1-13C,15N 141794-74-3 98%
    L-Alanine-1-13C,15N is the 13C- and 15N-labeled L-Alanine. L-Alanine is a non-essential amino acid, involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brain, and central nervous system.
    L-Alanine-1-13C,15N
  • HY-N0229S14
    L-Alanine-15N,d4 98%
    L-Alanine-15N,d4 is the deuterium and 15N-labeled L-Alanine. L-Alanine is a non-essential amino acid, involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brain, and central nervous system.
    L-Alanine-15N,d4
  • HY-N0378AGL
    D-Mannitol, M200 (GMP Like) 69-65-8
    D-Mannitol, M200 (GMP Like) (Mannitol, M200 (GMP Like)) is the GMP Like class D-Mannitol that can be used as pharmaceutical excipients. D-Mannitol (Mannitol) is an oral, resistant sugar widely used in the food and pharmaceutical industries to promote the absorption and retention of calcium and magnesium through cecal fermentation, while acting as a osmotic diuretic to reduce tissue edema. D-Mannitol can enhance brown fat formation, improve insulin effect, reduce blood sugar levels, And through the start the β3-adrenergic receptor (β3-AR), PGC1α and PKA induced by means of white fat cells into brown fat cells.
    D-Mannitol, M200 (GMP Like)
  • HY-N0378BGL
    D-Mannitol, M100 (GMP Like) 69-65-8 98%
    D-Mannitol, M100 (GMP Like) (Mannitol, M100 (GMP Like)) is the GMP Like class D-Mannitol that can be used as pharmaceutical excipients. D-Mannitol (Mannitol) is an oral, resistant sugar widely used in the food and pharmaceutical industries to promote the absorption and retention of calcium and magnesium through cecal fermentation, while acting as a osmotic diuretic to reduce tissue edema. D-Mannitol can enhance brown fat formation, improve insulin effect, reduce blood sugar levels, And through the start the β3-adrenergic receptor (β3-AR), PGC1α and PKA induced by means of white fat cells into brown fat cells.
    D-Mannitol, M100 (GMP Like)
  • HY-N0390S11
    L-Glutamine-2-13C 180991-02-0 98%
    L-Glutamine-2-13C is the 13C-labeled L-Glutamine. L-Glutamine (L-Glutamic acid 5-amide) is a non-essential amino acid present abundantly throughout the body and involved in many metabolic processes. L-Glutamine provides a source of carbons for oxidation in some cells.
    L-Glutamine-2-13C
  • HY-N0486S10
    L-Leucine-18O2 73579-45-0 98%
    L-Leucine-18O2 is the 18O-labeled L-Leucine. L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway.
    L-Leucine-18O2
Cat. No. Product Name / Synonyms Application Reactivity